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Low-Dose Naltrexone: Hype, Hope, or Homerun? | Sean Mackey, M.D., Ph.D. (Stanford Pain Medicine) This clip is from episode # 345 of The Drive which was released on 4/21/25. In the full episode, we discuss: -The role of antidepressants in pain management -Alternative therapies: acupuncture and cannabis -Fibromyalgia and chronic pain: clinical features, brain mechanisms, and emerging treatments like low-dose naltrexone -Possible brain benefits of low-dose naltrexone (LDN) for people with mild cogn
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FIBROMYALGIA PART 2: If your pain has never matched your test results, this might be the part that finally makes sense. Fibromyalgia is not diagnosed by a hunch or by “ruling everything else out”. There are real criteria that guide it. The Widespread Pain Index helps map out how many body regions are hurting. The Symptom Severity Scale measures fatigue, sleep quality, cognitive issues, and other physical symptoms that ride along with the pain. Normal labs and imaging do not exclude fibro, becaus
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TikTokaskpaindoc
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