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YouTubeThe Krusty Lab
The paradox of blocking BRAF #cancer #oncology #science
Why does BRAF inhibition sometimes fail? Understand the mechanism behind vemurafenib resistance. This breakdown explains how blocking BRAF can unintentionally cause ERK output to drop, lifting the suppression on RAS signalling. We trace how this network rerouting leads to RAS-driven tumour growth in patients undergoing targeted therapy ...
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