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MD Medicine Physician 🏥 on Instagram: "Prinzmetal Angina & Aspirin: What You Need to Know The Catch: Aspirin can sometimes worsen symptoms in Prinzmetal (Variant) Angina. Here’s why: 1. Unopposed alpha-receptor stimulation: Aspirin inhibits prostacyclin (a vasodilator) more than thromboxane A2 (a vasoconstrictor). This can lead to coronary vasoconstriction and exacerbate the spasm. 2. Potential for paradoxical response: In some cases, aspirin might not effectively manage the pain and could even
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MD Medicine Physician 🏥 on Instagram: "Prinzmetal Angina & …
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MD Medicine Physician 🏥 on Instagram: "ECG Challenge: Prinzmetal Angina vs STEMI! Prinzmetal (Variant) Angina: - Transient ST-elevation due to _coronary artery spasm_. - Chest pain at rest, often nocturnal, with normal coronary arteries on angiography. STEMI: - Persistent ST-elevation due to _plaque rupture and thrombosis_. - Chest pain with evidence of myocardial necrosis (elevated troponins). Key Difference: Prinzmetal = reversible spasm → treat with calcium channel blockers/nitrates. STEMI =
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