Other effective medicines are available for epilepsy and bipolar disorder and valproate should only be used if these don’t work or aren’t suitable for an individual patient. Image Credit: Medicines ...

Lithium and valproate are chemically unrelated compounds that are used to treat manic-depressive illness. Previously, we reported that lithium ions upregulate genes encoding proteins primarily ...

The Pharmacovigilance Risk Assessment Committee (PRAC) of the European Medicines Agency (EMA) has announced it is assessing new data on the potential risk of neurodevelopmental disorders (NDDs) in ...

Paternal use of the anti-seizure medication valproate during spermatogenesis was not associated with a risk of congenital malformations or neurodevelopmental disorders in offspring, an observational ...

Please provide your email address to receive an email when new articles are posted on . Absolute 10-year CKD risks were similar in both the lithium and valproate groups. Of more than 35,000 routine ...

The Medicines and Healthcare products Regulatory Agency (MHRA) has recommended that men taking valproate, and their female partners, should use effective contraception throughout the time they are on ...

In an animal study, researchers found that valproate, a common epilepsy drug, possessed hypnotic and antiepileptic properties during sleep, suggesting that the drug could help improve sleep quality ...

A system requiring sign off from two specialists to prescribe sodium valproate in patients under 55 years has had a significant impact on use of the drug, a study has found. The stricter approval ...

Families of children harmed by a drug that caused up to 20,000 babies to be born with disabilities have welcomed calls for compensation after their plight was compared to the thalidomide scandal. The ...