A research team led by the Hong Kong University of Science and Technology (HKUST) recently revealed how TMED10, a type of transmembrane protein, regulates muscle stem cell differentiation through ...
Microorganisms, such as baker's yeast, can be used as cell factories to produce different chemicals and proteins, such as commonly used pharmaceuticals as insulin. By modifying the cell factories ...
Box 1 Advances in live imaging for the study of the secretory pathway In recent years, several key live-imaging techniques have been developed that enable researchers to study the nuances of the ...
Eukaryotic cells are used as cell factories to produce and secrete multitudes of recombinant pharmaceutical proteins, including several of the current top-selling drugs. Due to the essential role and ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
Avenue Biosciences received $5.7 million in seed extension to scale a high-throughput protein engineering technology designed to accelerate the discovery of protein-based tools and therapies. Balnord ...
A novel reporter protein has been developed to enable the investigation of protein biogenesis in the ER and its disruption in disease. A recent research collaboration between multiple Japanese ...
A research team led by the Hong Kong University of Science and Technology (HKUST) recently revealed how TMED10, a type of transmembrane protein, regulates muscle stem cell differentiation through ...
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Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson's disease protein
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
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