It may have fewer than many of the other sciences, but biology does have two dozen or so “rules”—broad generalizations about the behavior or nature and evolution. Now, USC researchers want to add a ...
For a long time, evolutionary biologists have thought that the genetic mutations that drive the evolution of genes and proteins are largely neutral: they're neither good nor bad, but just ordinary ...
How do cells know what they should become as the body develops? Biological development depends crucially on spatial patterns: the lines that eventually give rise to segments, organs, or markings like ...
MPN-BP transformation is driven by sequential mutations disrupting genomic stability, with TP53 mutations being strong predictors of progression. TP53 mutations confer a selective growth advantage, ...
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New pangenomic approach enables unprecedented scaling for genetic data
Researchers at the University of California have created a novel data structure and compression method that allows ...
Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...
PanMAN data structures compress pangenomes massively, encode evolutionary histories, and enable scalable analysis of millions of genomes.
Two of the traits that set modern humans apart from non-human primates are taller stature and a higher basal metabolic rate. Researchers have identified a genetic variant that contributed to the ...
Engineers at the University of California have developed a new data structure and compression technique that enables the ...
Groundbreaking research shows that as men age, harmful genetic mutations in sperm become more common—not just from random chance, but because some are naturally favored. Advanced sequencing revealed ...
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