Previous studies have reported significant associations between schizophrenia and the dopamine receptor D2 gene (DRD2) variants. The relationships between DRD2 and clinical phenotypes are of ...

Although antipsychotic drugs are among the most widely prescribed medications, individuals with schizophrenia, bipolar disorder and autism-spectrum disorders often experience severe side effects ...

Two years ago at a scientific meeting, Bryan L. Roth of the University of North Carolina, Chapel Hill, announced that he and his colleagues were trying to solve the structure of the D 2 dopamine ...

Drinking in teens is a problem, no matter where in the world. A recent study in the Netherlands shows that individuals with a genetic variation in the DRD2 gene may be at increased risk of drinking to ...

Although antipsychotic drugs are among the most widely prescribed medications, individuals with schizophrenia, bipolar disorder and autism-spectrum disorders often experience severe side effects ...

Scientists at the University of North Carolina (UNC) at Chapel Hill have resolved the structure of the D 2 dopamine receptor (DRD2) bound to the antipsychotic drug risperidone. The researchers, led by ...

First-in-human biomarker-driven phase I trial of the potent and selective glutaminase-1 (GLS1) inhibitor IACS-6274 (IPN60090) in patients (pts) with molecularly selected advanced solid tumors. This is ...

In a study published in the Journal of Experimental Medicine, research groups led by Prof. Zhou Jiawei from the Institute of Neuroscience, Center for Excellence in Brain Science and Intelligence ...

Please provide your email address to receive an email when new articles are posted on . Researchers have discovered the first high-resolution crystal structure of the ...

A phase 1b/2 study of the combination of the IDO pathway inhibitor indoximod and temozolomide for adult patients with temozolomide-refractory primary malignant brain tumors: Safety analysis and ...